Storage in ultra-low-temperature decreases the levels of IgM anticardiolipin antibody in serum samples from tuberculosis patients

 

Authors
Ng, Alexandra; Weeks-Galindo, Cheyenne; Goodridge, Amador
Format
Article
Status
publishedVersion
Description

The evaluation of novel tuberculosis (TB) biomarkers relies on analysis of previously stored sample sets. We aimed to determine the effect of storage temperature on serum IgM anticardiolipin antibody levels in samples from TB patients. Ultra-low-temperature storage decreased IgM anticardiolipin levels. We recommend against using ultra-low-temperature storage when investigating IgM anticardiolipin biomarker-based tests.
The evaluation of novel tuberculosis (TB) biomarkers relies on analysis of previously stored sample sets. We aimed to determine the effect of storage temperature on serum IgM anticardiolipin antibody levels in samples from TB patients. Ultra-low-temperature storage decreased IgM anticardiolipin levels. We recommend against using ultra-low-temperature storage when investigating IgM anticardiolipin biomarker-based tests.

Publication Year
2014
Language
eng
Topic
Biomarker
IgM anti-cardiolipin
tuberculosis
storage temperature
therapy monitoring
Repository
RI INDICASAT
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http://repositorio-indicasat.org.pa/handle/123456789/145
Rights
openAccess
License